Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro
نویسندگان
چکیده
منابع مشابه
Profiling of Substrate Specificity of SARS-CoV 3CLpro
BACKGROUND The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-coronavirus is required for autoprocessing of the polyprotein, and is a potential target for treating coronaviral infection. METHODOLOGY/PRINCIPAL FINDINGS To obtain a thorough understanding of substrate specificity of the protease, a substrate library of 198 variants was created by performing saturation mutagenes...
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ژورنال
عنوان ژورنال: Journal of Enzyme Inhibition and Medicinal Chemistry
سال: 2020
ISSN: 1475-6366,1475-6374
DOI: 10.1080/14756366.2020.1801672